Description

4-Piperidinamine,3-Cyclopropyl-,Dihydrochloride,(3R,4R)-Rel-(9Ci) is a high-purity chiral piperidine derivative, specifically the (3R,4R)-rel enantiomer, supplied as its dihydrochloride salt. This compound serves as a critical chiral building block and advanced pharmaceutical intermediate for the synthesis of complex, biologically active molecules. It is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require enantiomerically defined scaffolds to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and antiviral drug candidates.
• Chiral Ligand Precursor: Used in the synthesis of chiral ligands for asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Agrochemical Research: Serves as a building block for developing new, enantiomerically pure pesticides and herbicides with improved efficacy and environmental profiles.
• Chemical Biology Probe: Utilized in medicinal chemistry to explore structure-activity relationships (SAR) and for target identification studies.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing high-value, complex organic molecules.

Basic Information

Product Name	4-Piperidinamine,3-Cyclopropyl-,Dihydrochloride,(3R,4R)-Rel-(9Ci)
CAS No.	444188-98-1
Molecular Formula	C8H18Cl2N2
Molecular Weight	213.15 g/mol
Synonyms	(3R,4R)-rel-3-Cyclopropyl-4-piperidinamine dihydrochloride; (3R,4R)-rel-3-Cyclopropylpiperidin-4-amine dihydrochloride; 3-Cyclopropyl-4-piperidinamine dihydrochloride (rel-(3R,4R)-); 4-Amino-3-cyclopropylpiperidine dihydrochloride (rel-(3R,4R)-); (rel-(3R,4R))-3-Cyclopropylpiperidin-4-amine dihydrochloride; 444188-98-1; 3-Cyclopropyl-4-piperidinamine hydrochloride (1:2)
EINECS	Contact for details

Quality Control

Our 4-Piperidinamine,3-Cyclopropyl-,Dihydrochloride,(3R,4R)-Rel-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric purity, NMR, and mass spectrometry for structural confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, identity, and relevant physical characteristics.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (rel-(3R,4R)-)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.