Description

3-Acetyl-6-Bromo-Quinoline-4-Carboxylic Acid is a high-purity, functionalized quinoline derivative that serves as a critical advanced intermediate in modern organic synthesis. Its unique molecular structure, featuring both acetyl and carboxylic acid functional groups on the quinoline core, makes it a versatile building block for constructing complex heterocyclic systems. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the research and development of new drug candidates, particularly for molecules targeting neurological disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinoline scaffold.
• Material Science Research: Serves as a building block for developing organic semiconductors, luminescent materials, and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Fine Chemical Production: Acts as a specialized intermediate for synthesizing dyes, pigments, and other performance chemicals.
• Academic & Contract Research: Essential for methodological development and discovery chemistry in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	3-Acetyl-6-Bromo-Quinoline-4-Carboxylic Acid
CAS No.	444112-84-9
Molecular Formula	C₁₂H₈BrNO₃
Molecular Weight	294.10 g/mol
Synonyms	6-Bromo-3-acetylquinoline-4-carboxylic acid; 4-Quinolinecarboxylic acid, 3-acetyl-6-bromo-; 3-Acetyl-6-bromoquinoline-4-carboxylic acid; 3-Acetyl-6-bromo-4-quinolinecarboxylic acid; 6-Bromo-3-acetyl-4-quinolinecarboxylic acid; 444112-84-9; 3-Acetyl-6-bromochinolin-4-carbonsäure (German)
EINECS	Contact for details

Quality Control

Our 3-Acetyl-6-Bromo-Quinoline-4-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.