Description

2-Chloro-n-(8-Quinolinyl)Benzamide CAS NO 444112-59-8 is a specialized organic compound featuring a benzamide core linked to a quinoline moiety, a structure of significant interest in advanced chemical synthesis. This compound serves as a critical high-purity building block for research and development in pharmaceutical and agrochemical discovery. It is primarily utilized by R&D chemists and process development scientists working on novel active ingredients, particularly in the areas of medicinal chemistry and crop protection.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibitors or receptor modulators.
• Agrochemical Research: Serves as a core scaffold for developing new herbicides, fungicides, or insecticides with potentially novel modes of action.
• Chemical Biology Probe: Used in academic and industrial research to study biological pathways and protein-ligand interactions due to its distinctive heterocyclic structure.
• Material Science Research: Potential building block for creating advanced organic materials, such as ligands for catalysts or components in organic electronics.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	2-Chloro-n-(8-Quinolinyl)Benzamide
CAS No.	444112-59-8
Molecular Formula	C₁₆H₁₁ClN₂O
Molecular Weight	282.72 g/mol
Synonyms	N-(8-Quinolyl)-2-chlorobenzamide; 2-Chloro-N-quinolin-8-yl-benzamide; 2-Chlorobenzoic acid 8-quinolylamide; 8-Quinolinamine, N-(2-chlorobenzoyl)-; Benzamide, 2-chloro-N-8-quinolinyl-; 2-Chloro-N-(quinolin-8-yl)benzamide
EINECS	Contact for details

Quality Control

Our 2-Chloro-n-(8-Quinolinyl)Benzamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, essential for sensitive R&D applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our standard quality commitment aligns with research-grade and custom synthesis requirements, and specifications can be adjusted to meet specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.