Description

Spiro[Cyclopentane-1,2(3H)-Indolizin]-7(1H)-One, Tetrahydro- (9Ci) is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic indolizine core structure. This compound is of significant value for its role as a critical building block in the synthesis of complex bioactive molecules and novel drug candidates. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor for the development of new active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold in drug discovery programs for building molecular libraries and exploring structure-activity relationships (SAR).
• Agrochemical Synthesis: Employed in the research and development of novel pesticides and herbicides due to its complex heterocyclic framework.
• Organic Synthesis Building Block: Utilized in academic and industrial laboratories for the construction of complex natural product analogs and other fine chemicals.
• Process Chemistry Development: Acts as a starting material or intermediate in the scale-up and optimization of synthetic routes for commercial production.

Basic Information

Product Name	Spiro[Cyclopentane-1,2(3H)-Indolizin]-7(1H)-One, Tetrahydro- (9Ci)
CAS No.	443984-31-4
Molecular Formula	C12H15NO
Molecular Weight	189.25 g/mol
Synonyms	Tetrahydrospiro[cyclopentane-1,2(3H)-indolizin]-7(1H)-one; 1H-Spiro[cyclopentane-1,2'-indolizin]-7'(3'H)-one, tetrahydro-; Spiro[cyclopentane-1,2'-indolizine]-7'(1'H)-one, tetrahydro-; CAS 443984-31-4; Tetrahydrospirocyclopentaneindolizinone; Advanced Spirocyclic Intermediate
EINECS	Contact for details

Quality Control

Our production of Spiro[Cyclopentane-1,2(3H)-Indolizin]-7(1H)-One, Tetrahydro- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials are subjected to rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.