Description

Benzamide, 2-Chloro-n-[2-(4-Ethyl-1-Piperazinyl)-4-Methyl-6-Quinolinyl]- is a specialized quinoline derivative with a piperazine substituent, representing a high-value synthetic intermediate in advanced organic chemistry. This compound is critical for research and development in medicinal chemistry, particularly for its potential role in modulating biological targets. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the research and synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Biochemical Tool Compound: Employed in vitro and in vivo studies to investigate specific enzyme inhibition or receptor modulation pathways.
• Fine Chemical Synthesis: Utilized in multi-step organic synthesis for constructing complex nitrogen-containing heterocycles with potential biological activity.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	Benzamide, 2-Chloro-n-[2-(4-Ethyl-1-Piperazinyl)-4-Methyl-6-Quinolinyl]-
CAS No.	442898-56-8
Molecular Formula	C23H25ClN4O
Molecular Weight	408.93 g/mol
Synonyms	2-Chloro-N-[2-(4-ethylpiperazin-1-yl)-4-methylquinolin-6-yl]benzamide; 2-Chloro-N-[2-(4-ethyl-1-piperazinyl)-4-methyl-6-quinolinyl]benzamide; 442898-56-8; Benzamide, 2-chloro-N-[2-(4-ethyl-1-piperazinyl)-4-methyl-6-quinolinyl]-; 6-Quinolinamine, N-(2-chlorobenzoyl)-2-(4-ethyl-1-piperazinyl)-4-methyl-; N-(2-Chlorobenzoyl)-2-(4-ethylpiperazin-1-yl)-4-methylquinolin-6-amine
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development projects with custom purity grades and analytical method development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.