Description

2H-Indol-2-One,5-Fluoro-1,3-Dihydro-3-Methylene-(9Ci) is a specialized fluorinated indole derivative, a high-value synthetic intermediate prized for its unique molecular scaffold. This compound is critical for research and development in advanced organic synthesis, enabling the construction of complex molecules with targeted biological activity. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on developing novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging the biological activity of the fluorinated indole core.
• Organic Synthesis & Material Science: Acts as a precursor for synthesizing complex heterocyclic compounds and functional materials for electronic or photonic applications.
• Biochemical Probe Development: Employed in medicinal chemistry to create molecular probes for studying enzyme mechanisms and biological pathways.
• Contract Research & Development (CRO/CMO): Supplied to research organizations and custom synthesis facilities for client-directed projects.

Basic Information

Product Name	2H-Indol-2-One,5-Fluoro-1,3-Dihydro-3-Methylene-(9Ci)
CAS No.	442883-73-0
Molecular Formula	C9H6FNO
Molecular Weight	163.15 g/mol
Synonyms	5-Fluoro-3-methylene-1,3-dihydro-2H-indol-2-one; 5-Fluoro-3-methylidene-1,3-dihydro-2H-indol-2-one; 5-Fluoro-3-methyleneoxindole; 3-Methylene-5-fluorooxindole; 442883-73-0; 2H-Indol-2-one, 5-fluoro-1,3-dihydro-3-methylene- (9CI); 5-Fluoro-3-methylideneindolin-2-one
EINECS	Contact for details

Quality Control

Our production of 2H-Indol-2-One,5-Fluoro-1,3-Dihydro-3-Methylene-(9Ci) adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications. Our facilities operate under cGMP principles suitable for advanced intermediate synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.