Description

5-(2,5-Dimethoxyphenyl)-3-(4-methoxyphenyl)-1-(methylsulfonyl)-4,5-dihydro-1H-pyrazole is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound matters because it provides a critical, structurally defined building block essential for research and development in modern medicinal chemistry, ensuring precise molecular architecture. It is primarily needed by pharmaceutical R&D laboratories, contract research and manufacturing organizations (CROs/CMOs), and fine chemical producers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Synthesis Building Block: Used in multi-step organic synthesis to construct more complex heterocyclic systems with potential biological activity.
• Reference Standard: Employed as an analytical standard for quality control and method development in API manufacturing processes.
• Academic & Industrial R&D: Utilized in university and corporate research laboratories for exploring new chemical entities and reaction methodologies.

Basic Information

Product Name	5-(2,5-Dimethoxyphenyl)-3-(4-Methoxyphenyl)-1-(Methylsulfonyl)-4,5-Dihydro-1H-Pyrazole
CAS No.	442650-14-8
Molecular Formula	C19H22N2O5S
Molecular Weight	390.45 g/mol
Synonyms	1-(Methylsulfonyl)-5-(2,5-dimethoxyphenyl)-3-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazole; 4,5-Dihydro-1H-pyrazole, 5-(2,5-dimethoxyphenyl)-3-(4-methoxyphenyl)-1-(methylsulfonyl)-; CAS 442650-14-8; 1-Methanesulfonyl-5-(2,5-dimethoxyphenyl)-3-(4-methoxyphenyl)-4,5-dihydropyrazole; Pyrazole sulfone derivative (2,5,4'-trimethoxy substituted); 5-(2,5-Dimethoxyphenyl)-3-(p-methoxyphenyl)-1-(methylsulfonyl)-4,5-dihydro-1H-pyrazole
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific test results are available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.