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2-Deoxy-2-Fluoro-D-Glucose 6-Phosphate Dipotassium Salt CAS NO 441764-08-5
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CAS No.:441764-08-5
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-Deoxy-2-Fluoro-D-Glucose 6-Phosphate Dipotassium Salt is a critical phosphorylated derivative of the widely used PET tracer, 2-Fluoro-2-deoxy-D-glucose (FDG). This compound serves as a key biochemical precursor and reference standard in the development and validation of radiopharmaceuticals and metabolic research. It is essential for researchers and manufacturers in nuclear medicine, oncology research, and molecular imaging, providing a stable, non-radioactive standard for quality control and assay development.
Application
- Radiopharmaceutical Precursor: A vital non-radioactive intermediate in the synthesis of [18F]FDG for Positron Emission Tomography (PET) imaging.
- Biochemical Research Standard: Used as a high-purity reference standard in studies of glucose metabolism, hexokinase activity, and glycolytic pathways.
- Diagnostic Kit Development: Employed in the formulation and quality control of kits for the on-site production of PET tracers.
- Oncology and Neurology Research: Facilitates in vitro studies investigating tumor metabolism and brain glucose utilization.
- Enzyme Kinetics Studies: Acts as a substrate or inhibitor in enzymatic assays, particularly for kinases and phosphatases involved in carbohydrate metabolism.
- Pharmaceutical Impurity Profiling: Serves as a certified reference material for identifying and quantifying related substances in FDG-based products.
Basic Information
| Item | Details |
|---|---|
| Product Name | 2-Deoxy-2-Fluoro-D-Glucose 6-Phosphate Dipotassium Salt |
| CAS No. | 441764-08-5 |
| Molecular Formula | C6H11FO9P·2K |
| Molecular Weight | 364.32 g/mol |
| Synonyms | 2-Fluoro-2-deoxy-D-glucose 6-phosphate dipotassium salt; FDG-6-P dipotassium salt; 2-Deoxy-2-fluoro-D-glucose-6-phosphate K2; 6-O-Phosphono-2-deoxy-2-fluoro-D-glucopyranose dipotassium salt; 2-FDG-6P dipotassium; Fluorodeoxyglucose 6-phosphate dipotassium; D-Glucose, 2-deoxy-2-fluoro-, 6-(dihydrogen phosphate), dipotassium salt |
| EINECS | Contact for details |
Quality Control
Every batch of our 2-Deoxy-2-Fluoro-D-Glucose 6-Phosphate Dipotassium Salt is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, meeting the exacting requirements for research and pharmaceutical development. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting key parameters such as assay, impurity profile, and residual solvent content.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic nature, the container should be allowed to equilibrate to room temperature before opening to minimize moisture uptake. For long-term storage, consider desiccants or under an inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Assay (HPLC) | ≥ 95.0% |
| Purity (HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 5.0% |
| Heavy Metals | ≤ 20 ppm |
| Residual Solvents (GC) | Meets ICH guidelines |
| Specific Rotation | Contact for details |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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