Description

Methyl 3-Amino-2-(Aminomethyl)Propanoate Dihydrochloride is a high-purity, protected amino acid derivative primarily used as a critical building block in advanced organic synthesis. Its dihydrochloride salt form enhances stability and handling, making it a valuable reagent for research and industrial-scale production. This compound is essential for pharmaceutical chemists and R&D professionals developing novel peptides, active pharmaceutical ingredients (APIs), and complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly in peptide and peptidomimetic chemistry.
• Peptide Synthesis: Serves as a protected amino acid ester building block for solid-phase and solution-phase peptide synthesis (SPPS).
• Chemical Research & Development: Used in academic and industrial R&D for constructing novel molecular scaffolds and exploring structure-activity relationships (SAR).
• API Manufacturing: Employed in the production of Active Pharmaceutical Ingredients (APIs) requiring specific, branched-chain amino acid motifs.
• Bioconjugation Chemistry: Useful for introducing amine-functionalized linkers in the development of antibody-drug conjugates (ADCs) and other bioconjugates.
• Agrochemical Synthesis: Potential intermediate in the development of specialized herbicides or plant growth regulators with amino acid-based structures.

Basic Information

Product Name	Methyl 3-Amino-2-(Aminomethyl)Propanoate Dihydrochloride
CAS No.	440644-06-4
Molecular Formula	C6H15Cl2N2O2
Molecular Weight	218.10 g/mol
Synonyms	Methyl 3-amino-2-(aminomethyl)propionate dihydrochloride; 2-(Aminomethyl)-3-aminopropanoic acid methyl ester dihydrochloride; 3-Amino-2-(aminomethyl)propionic acid methyl ester dihydrochloride; Methyl β-amino-β-(aminomethyl)propionate dihydrochloride; Methyl 3,3-diaminoisobutyrate dihydrochloride; 3,3-Diaminoisobutyric acid methyl ester dihydrochloride; 3-Amino-2-(aminomethyl)propanoic acid methyl ester hydrochloride (1:2)
EINECS	Contact for details

Quality Control

Our Methyl 3-Amino-2-(Aminomethyl)Propanoate Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and research applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.