Description

1-(Aminomethyl)Cyclobutanamine Dihydrochloride is a high-purity, versatile diamine building block with significant utility in advanced organic synthesis. Its unique cyclobutane core and dual amine functionality make it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and plant growth regulators, leveraging its rigid cyclic structure.
• Ligand and Catalyst Development: Employed in the creation of chelating ligands for metal catalysts used in asymmetric synthesis and polymerization reactions.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for producing specialty polyamides, polyurethanes, and epoxy resins with enhanced thermal and mechanical properties.
• Chemical Research: A valuable scaffold in academic and industrial R&D for exploring structure-activity relationships (SAR) and developing new chemical entities.
• Peptide Mimetics: Incorporated into peptide analogs to introduce conformational constraints, improving metabolic stability and biological activity.

Basic Information

Product Name	1-(Aminomethyl)Cyclobutanamine Dihydrochloride
CAS No.	440100-10-7
Molecular Formula	C6H15N2Cl2 or C6H14N2·2HCl
Molecular Weight	199.11 g/mol
Synonyms	1-(Aminomethyl)cyclobutanamine dihydrochloride; Cyclobutanemethanamine, 1-(aminomethyl)-, dihydrochloride; 1-(Aminomethyl)cyclobutan-1-amine dihydrochloride; 1,1-Bis(aminomethyl)cyclobutane dihydrochloride; 1,1-Cyclobutanedimethanamine dihydrochloride; (1-Aminocyclobutyl)methanamine dihydrochloride; 440100-10-7
EINECS	Contact for details

Quality Control

Our 1-(Aminomethyl)Cyclobutanamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.