Description

5-(Carboxymethyl)-1-[4-(Trifluoromethoxy)Phenyl]-1H-1,2,3-Triazole-4-Carboxylic Acid is a high-purity, multifunctional triazole derivative designed for advanced chemical synthesis. This compound matters as a critical pharmaceutical intermediate and organic building block, offering a unique trifluoromethoxy-substituted aromatic system for developing novel active ingredients. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate sophisticated heterocyclic motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Research: Serves as a building block for developing new generation herbicides, fungicides, and insecticides with enhanced activity and selectivity.
• Ligand Synthesis: Used in coordination chemistry for creating specialized ligands in catalysis and material science applications.
• Peptide Mimetics & Conjugation: The carboxylic acid groups enable its use in constructing peptide analogs or for bioconjugation strategies in probe and therapeutic agent development.
• Material Science: Incorporated into polymers or organic frameworks to impart specific electronic or surface properties.
• Chemical Biology Probe Development: Utilized as a scaffold for creating activity-based probes or inhibitors for enzyme studies.

Basic Information

Product Name	5-(Carboxymethyl)-1-[4-(Trifluoromethoxy)Phenyl]-1H-1,2,3-Triazole-4-Carboxylic Acid
CAS No.	439095-12-2
Molecular Formula	C12H8F3N3O5
Molecular Weight	331.21 g/mol
Synonyms	1-[4-(Trifluoromethoxy)phenyl]-1H-1,2,3-triazole-4,5-dicarboxylic acid, 5-(carboxymethyl) derivative; 4,5-Bis(carboxymethyl)-1-(4-trifluoromethoxyphenyl)-1,2,3-triazole (common misnomer); 1-(4-Trifluoromethoxyphenyl)-1H-1,2,3-triazole-4,5-dicarboxylic acid, 5-methyl ester (related ester); TFMP-Triazole-dicarboxylic Acid; CAS 439095-12-2
EINECS	Contact for details

Quality Control

Our 5-(Carboxymethyl)-1-[4-(Trifluoromethoxy)Phenyl]-1H-1,2,3-Triazole-4-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting R&D and process chemistry standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.