Description

Benzoic Acid, 2-Chloro-4,5-Difluoro-, Hydrazide (9Ci) is a specialized aromatic hydrazide derivative, a high-purity intermediate of significant interest in advanced synthetic chemistry. Its precise molecular architecture, featuring chloro and difluoro substitutions, makes it a valuable precursor for constructing complex heterocyclic systems and active pharmaceutical ingredients (APIs). This compound is essential for R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology applications.
• Agrochemical Synthesis: Used as a precursor in the development of new-generation herbicides, fungicides, and insecticides, leveraging its halogenated aromatic core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Heterocyclic Chemistry: Fundamental for constructing pyrazole, triazole, and other nitrogen-containing heterocycles prevalent in bioactive molecules.
• Material Science Research: Investigated as a monomer or functional additive in the development of polymers and advanced organic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	Benzoic Acid, 2-Chloro-4,5-Difluoro-, Hydrazide (9Ci)
CAS No.	438530-91-7
Molecular Formula	C7H5ClF2N2O
Molecular Weight	206.58 g/mol
Synonyms	2-Chloro-4,5-difluorobenzoic hydrazide; 2-Chloro-4,5-difluorobenzohydrazide; (2-Chloro-4,5-difluorobenzoyl)hydrazine; Benzoic acid, 2-chloro-4,5-difluoro-, hydrazide; 438530-91-7; 2-Chloro-4,5-difluorobenzoyl hydrazide; 2-Chloro-4,5-difluorobenzoic acid hydrazide
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 2-Chloro-4,5-Difluoro-, Hydrazide (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP, ICH Q7 guidelines, and relevant pharmacopeial standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended. Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.