Description

n-Alloc-N'-Boc-Ethylenediamine is a high-purity, bifunctional amine protecting group reagent, specifically engineered for advanced organic synthesis. This compound is critical for researchers and manufacturers requiring precise, orthogonal protection strategies for primary amine functionalities. It is primarily utilized in the pharmaceutical and biotechnology sectors for the synthesis of complex molecules, including peptides, peptidomimetics, and active pharmaceutical ingredients (APIs).

Application

• Peptide Synthesis: Serves as a key building block for introducing orthogonally protected diamine linkers in solid-phase and solution-phase peptide synthesis.
• Pharmaceutical Intermediates: Used in the multi-step synthesis of complex drug candidates, particularly those requiring selective amine protection and deprotection sequences.
• Bioconjugation: Acts as a versatile linker for coupling biomolecules (e.g., proteins, antibodies) to drugs, dyes, or other functional groups in ADC (Antibody-Drug Conjugate) development.
• Chemical Biology Probes: Employed in the creation of labeled probes and tools for studying biological processes and enzyme activity.
• Polymer Chemistry: Can be used as a monomer or modifier for creating functionalized polymers with amine-reactive sites.
• Combinatorial Chemistry: A valuable reagent for generating diverse chemical libraries in drug discovery platforms.

Basic Information

Product Name	n-Alloc-N'-Boc-Ethylenediamine
CAS No.	438012-35-2
Molecular Formula	C₁₂H₂₂N₂O₄
Molecular Weight	258.31 g/mol
Synonyms	N-Alloc-N'-Boc-ethylenediamine; N-(tert-Butoxycarbonyl)-N'-(allyloxycarbonyl)ethylenediamine; 1-[(Allyloxy)carbonyl]-2-[(tert-butoxycarbonyl)amino]ethane; 2-[(tert-Butoxycarbonyl)amino]ethyl allylcarbamate; Boc-NH-CH2-CH2-NH-Alloc; Ethylenediamine, N-allyloxycarbonyl-N'-tert-butoxycarbonyl-; (2-{[(Allyloxy)carbonyl]amino}ethyl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our n-Alloc-N'-Boc-Ethylenediamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided to guarantee consistency and reliability for your critical research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.