Description

Phenol, 2-[(2S)-3-Amino-2-Hydroxypropoxy]- (9Ci) is a specialized chiral phenolic compound featuring both amino and hydroxypropoxy functional groups. This unique structure makes it a valuable chiral building block and intermediate for the synthesis of complex bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in areas requiring stereochemical control.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), especially β-blockers and other adrenergic agents.
• Asymmetric Synthesis: Utilized as a precursor or ligand in catalytic asymmetric reactions to induce stereoselectivity.
• Bioconjugation & Linker Chemistry: The phenolic and amino groups enable its use in creating cleavable linkers for drug delivery systems or bioconjugation protocols.
• Chemical Biology Research: Serves as a scaffold or probe in medicinal chemistry for studying enzyme interactions and receptor binding.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural products and other high-value specialty chemicals.

Basic Information

Product Name	Phenol, 2-[(2S)-3-Amino-2-Hydroxypropoxy]- (9Ci)
CAS No.	437765-36-1
Molecular Formula	C9H13NO3
Molecular Weight	183.20 g/mol
Synonyms	(S)-2-(3-Amino-2-hydroxypropoxy)phenol; 2-[(2S)-3-Amino-2-hydroxypropoxy]phenol; 1-Amino-3-(2-hydroxyphenoxy)-2-propanol, (S)-; (S)-1-Amino-3-(2-hydroxyphenoxy)-2-propanol; (S)-2-(3-Amino-2-hydroxypropoxy)phenol; 437765-36-1; (S)-Isomer of a phenolic β-amino alcohol
EINECS	Contact for details

Quality Control

We maintain stringent quality control for this advanced intermediate, with typical purity levels meeting or exceeding 97% (HPLC). Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing chiral purity, chemical identity, and impurity profiles. Our quality systems support development and cGMP manufacturing needs, ensuring reliable batch-to-batch consistency for your critical research and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) to minimize oxidation and degradation. This material is hygroscopic and light-sensitive; ensure containers are kept sealed in a cool, dry, and well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.