Description

Ruthenium, Dichloro[1,3-Dihydro-1,3-Bis(2,4,6-Trimethylphenyl)-2H-Imidazol-2-Ylidene][(2-Oxo-1-Pyrrolidinyl)Methylene](Tricyclohexylphosphine)-, (Sp-5-41)- (9Ci) is a highly specialized, second-generation Grubbs-Hoveyda type ruthenium metathesis catalyst. This compound matters for its exceptional activity and selectivity in challenging olefin metathesis reactions, including cross-metathesis (CM), ring-closing metathesis (RCM), and ring-opening metathesis polymerization (ROMP). It is an essential tool for researchers and process chemists in pharmaceutical development, advanced material science, and specialty chemical synthesis, where precise control over molecular architecture is required.

Application

• Pharmaceutical Intermediate Synthesis: Enabling the efficient construction of complex, biologically active macrocycles and strained ring systems via ring-closing metathesis (RCM).
• Advanced Polymer & Material Science: Facilitating the synthesis of novel polymers with tailored properties through ring-opening metathesis polymerization (ROMP) and acyclic diene metathesis (ADMET) polymerization.
• Fine Chemical & Agrochemical Manufacturing: Used in the production of high-value specialty chemicals, flavors, fragrances, and agrochemical intermediates via cross-metathesis (CM) reactions.
• Academic & Industrial R&D: Serving as a critical reagent for methodology development and exploring new synthetic pathways in organic and organometallic chemistry.
• Cross-Coupling & Tandem Catalysis: Potential use in tandem catalytic systems or for the synthesis of ligands and precursors for other transition-metal catalyzed processes.

Basic Information

Item	Detail
Product Name	Ruthenium, Dichloro[1,3-Dihydro-1,3-Bis(2,4,6-Trimethylphenyl)-2H-Imidazol-2-Ylidene][(2-Oxo-1-Pyrrolidinyl)Methylene](Tricyclohexylphosphine)-, (Sp-5-41)- (9Ci)
CAS No.	437757-12-5
Molecular Formula	C46H66Cl2N3OPRu
Molecular Weight	889.98 g/mol
Synonyms	Grubbs-Hoveyda II Catalyst; Hoveyda-Grubbs Catalyst 2nd Generation; (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(o-isopropoxyphenylmethylene)ruthenium (common misnomer for related structure); Dichloro[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene][(2-oxo-1-pyrrolidinyl)methylene](tricyclohexylphosphine)ruthenium; Zhan Catalyst 1B; Ru-based Olefin Metathesis Catalyst; CAS 437757-12-5.
EINECS	Contact for details

Quality Control

Every batch of our ruthenium metathesis catalyst is synthesized and handled under strict inert atmosphere conditions to ensure maximum activity and shelf-life. We employ advanced analytical techniques including NMR (1H, 13C, 31P) and HPLC for identity confirmation and purity assessment. A comprehensive Certificate of Analysis (COA) detailing batch-specific data is provided with each shipment, ensuring traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to maintain stability and prevent decomposition. This material is easily oxidized and moisture-sensitive; ensure containers are sealed immediately after use and stored in a cool, dry, and well-ventilated area.

Specification

Item	Specification
Appearance	Dark purple to brown crystalline solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Solubility	Soluble in common organic solvents (DCM, toluene, THF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.