Description

3-(3,5-Dioxo-4-Azatetracyclo[5.3.2.0(2,6).0(8,10)]Dodec-11-En-4-Yl)Propanoic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its complex, rigid polycyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and anti-inflammatory pathways. It is primarily required by research institutions and pharmaceutical manufacturers engaged in cutting-edge drug discovery and process development.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug candidates, especially for neurological and anti-inflammatory applications.
• Organic Synthesis Building Block: Used in research-scale and pilot-scale organic chemistry for constructing novel molecular architectures with specific stereochemistry.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to develop new therapeutic agents with improved efficacy and safety profiles.
• Process Chemistry Development: Utilized for optimizing synthetic routes, scaling up production, and developing robust manufacturing processes for new APIs.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	3-(3,5-Dioxo-4-Azatetracyclo[5.3.2.0(2,6).0(8,10)]Dodec-11-En-4-Yl)Propanoic Acid
CAS No.	436811-18-6
Molecular Formula	C15H15NO4
Molecular Weight	273.28 g/mol
Synonyms	4-Azatetracyclo[5.3.2.0²,⁶.0⁸,¹⁰]dodec-11-ene-4-propanoic acid, 3,5-dioxo-; 3-(3,5-Dioxo-4-azatetracyclo[5.3.2.0²,⁶.0⁸,¹⁰]dodec-11-en-4-yl)propanoic acid; Propanoic acid, 3-(3,5-dioxo-4-azatetracyclo[5.3.2.0²,⁶.0⁸,¹⁰]dodec-11-en-4-yl)-; Advanced Pharmaceutical Intermediate 436811-18-6; Polycyclic Lactam Propanoic Acid Derivative
EINECS	Contact for details

Quality Control

Our 3-(3,5-Dioxo-4-Azatetracyclo[5.3.2.0(2,6).0(8,10)]Dodec-11-En-4-Yl)Propanoic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Production adheres to cGMP (current Good Manufacturing Practice) guidelines where applicable. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.