Description

6-Ethyl-2-Thien-2-Ylquinoline-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily needed by R&D laboratories, pharmaceutical manufacturers, and fine chemical producers engaged in developing new drug candidates, especially within medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting complex disease pathways.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Used in the construction of complex heterocyclic systems for advanced material science and specialty chemical applications.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Reference Standard: Utilized as an analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	6-Ethyl-2-Thien-2-Ylquinoline-4-Carboxylic Acid
CAS No.	436092-61-4
Molecular Formula	C₁₆H₁₃NO₂S
Molecular Weight	283.35 g/mol
Synonyms	6-Ethyl-2-(thiophen-2-yl)quinoline-4-carboxylic acid; 2-(2-Thienyl)-6-ethyl-4-quinolinecarboxylic acid; 4-Quinolinecarboxylic acid, 6-ethyl-2-(2-thienyl)-; 6-Ethyl-2-(2-thienyl)quinoline-4-carboxylic acid; ETQCA; CAS 436092-61-4
EINECS	Contact for details

Quality Control

Our 6-Ethyl-2-Thien-2-Ylquinoline-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with customer specifications and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.