Description

Lecozotan CAS NO 434283-16-6 is a selective serotonin 1A (5-HT1A) receptor antagonist with high research and pharmaceutical significance. This compound is a critical tool for neuropharmacological studies, particularly in investigating the role of serotonin receptors in mood, anxiety, and cognitive disorders. It is primarily utilized by pharmaceutical R&D departments, academic research institutions, and contract research organizations (CROs) engaged in central nervous system (CNS) drug discovery and development.

Application

• Neuropharmacological Research: A key reference standard for studying the function and modulation of 5-HT1A receptors in the brain.
• Drug Discovery & Development: Used as a pharmacological tool in preclinical studies for potential antidepressants, anxiolytics, and cognitive enhancers.
• Mechanism of Action Studies: Helps elucidate the complex signaling pathways and behavioral effects associated with serotonin receptor activity.
• Biochemical Assay Development: Serves as a standard compound in high-throughput screening (HTS) and receptor binding assays.
• Academic & Clinical Research: Supports investigations into the neurobiological basis of psychiatric and neurological conditions.
• Reference Material: Provides a certified, high-purity standard for analytical method development and validation in quality control laboratories.

Basic Information

Product Name	Lecozotan
CAS No.	434283-16-6
Molecular Formula	C23H28N4O2S
Molecular Weight	424.56 g/mol
Synonyms	SRA-333; Lecozotan hydrochloride; (2R)-2-[[4-[(2,3-Dihydro-1,4-benzodioxin-5-yl)methyl]-1-piperazinyl]methyl]-1,2,3,4-tetrahydro-7-isoquinolinecarboxamide; SRA 333; 5-HT1A Receptor Antagonist SRA-333; 1,2,3,4-Tetrahydro-7-isoquinolinecarboxamide, 2-[[4-[(2,3-dihydro-1,4-benzodioxin-5-yl)methyl]-1-piperazinyl]methyl]-, (2R)-
EINECS	Contact for details

Quality Control

Our Lecozotan is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, generated using validated analytical methods such as HPLC, NMR, and mass spectrometry. We adhere to relevant industry standards for research chemicals to guarantee reliable and reproducible results for your scientific work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.