Description

3-Amino-5-Bromo-2-Nitropyridine is a versatile heterocyclic building block of significant importance in advanced organic synthesis. Its unique structure, featuring amino, bromo, and nitro substituents on a pyridine core, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides due to its reactive halogen and nitro groups.
• Material Science Precursor: Serves as a starting material for creating functionalized ligands, dyes, and photoactive compounds.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig amination.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D exploring new heterocyclic chemistry and reaction pathways.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	3-Amino-5-Bromo-2-Nitropyridine
CAS No.	433226-05-2
Molecular Formula	C5H4BrN3O2
Molecular Weight	218.01 g/mol
Synonyms	5-Bromo-2-nitro-3-pyridinamine; 3-Pyridinamine, 5-bromo-2-nitro-; 5-Bromo-2-nitro-pyridin-3-ylamine; 5-Bromo-3-amino-2-nitropyridine; 2-Nitro-5-bromo-3-aminopyridine; 3-Amino-5-bromo-2-nitropyridine; 5-Bromo-3-amino-2-nitropyridine; 433226-05-2
EINECS	Contact for details

Quality Control

Our 3-Amino-5-Bromo-2-Nitropyridine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in a dark place.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.