Description

Spiro[Aziridine-2,3(4H)-[2H-1]Benzopyran]-4-One, 3-Ethyl-, (2R,3R)-Rel- (9Ci) is a high-purity, stereochemically defined spirocyclic compound containing an aziridine moiety fused to a benzopyranone scaffold. This specific chiral structure makes it a valuable and sophisticated building block for advanced organic synthesis, particularly in the development of novel pharmaceuticals and bioactive molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating complex molecular architectures with potential biological activity.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of potential drug candidates, especially those targeting neurological or oncological pathways.
• Agrochemical Research: Used in the development of novel pesticides or herbicides where the spirocyclic and aziridine structures may confer unique biological properties.
• Asymmetric Synthesis: Employed as a chiral auxiliary or scaffold in stereoselective reactions to construct complex molecules with high enantiomeric purity.
• Medicinal Chemistry: Utilized in structure-activity relationship (SAR) studies and library synthesis for hit-to-lead optimization.
• Chemical Biology Probe Development: Acts as a core structure for creating molecular probes to study enzyme mechanisms or protein interactions.
• Academic & Institutional Research: Used in universities and R&D institutes for methodological development in organic chemistry and heterocyclic compound synthesis.

Basic Information

Item	Details
Product Name	Spiro[Aziridine-2,3(4H)-[2H-1]Benzopyran]-4-One, 3-Ethyl-, (2R,3R)-Rel- (9Ci)
CAS No.	432029-80-6
Molecular Formula	C13H13NO2
Molecular Weight	215.25 g/mol
Synonyms	rel-(2R,3R)-3-Ethylspiro[aziridine-2,3'(4'H)-[2H]chromene]-4'-one; (2R,3R)-rel-3-Ethyl-2,3-dihydro-2H-spiro[azirine-2,1'-isochromene]-4'(3'H)-one; 3-Ethylspiro[aziridine-2,3'(4'H)-[2H]chromene]-4'-one, (2R,3R)-rel-; Spiro[aziridine-2,3(4H)-[2H-1]benzopyran]-4-one, 3-ethyl-, (2R,3R)-rel-; CAS 432029-80-6; Aziridine-fused benzopyranone derivative; Chiral spirocyclic aziridine.
EINECS	Contact for details

Quality Control

Our Spiro[Aziridine-2,3(4H)-[2H-1]Benzopyran]-4-One, 3-Ethyl-, (2R,3R)-Rel- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing including HPLC for purity and chiral purity, NMR, and MS for structural confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications. Our quality commitment supports applications requiring high stereochemical fidelity and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation, the container should be sealed immediately after use to minimize exposure to air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.