Description

Spiro[Aziridine-2,3(4H)-[2H-1]Benzopyran]-4-One, 3-Ethyl-, (2R,3S)-Rel- (9Ci) is a high-purity, stereochemically defined spirocyclic compound featuring fused aziridine and benzopyran motifs. This complex molecular architecture makes it a valuable and versatile chiral building block for advanced organic synthesis and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel, biologically active molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) or anti-infective drug candidates.
• Agrochemical Synthesis: Used as a precursor in the design and synthesis of novel herbicides, fungicides, or insecticides with specific stereochemical requirements.
• Asymmetric Catalysis Ligand Precursor: The rigid spirocyclic and aziridine structure can be modified to develop novel chiral ligands or organocatalysts for asymmetric transformations.
• Chemical Biology Probe: Employed in academic and industrial research to create molecular probes for studying enzyme mechanisms or protein-ligand interactions due to its reactive aziridine ring.
• Material Science Research: Investigated as a monomer or precursor for synthesizing specialized polymers with unique optical or mechanical properties.

Basic Information

Item	Detail
Product Name	Spiro[Aziridine-2,3(4H)-[2H-1]Benzopyran]-4-One, 3-Ethyl-, (2R,3S)-Rel- (9Ci)
CAS No.	432029-79-3
Molecular Formula	C13H15NO2
Molecular Weight	217.26 g/mol
Synonyms	rel-(2R,3S)-3-Ethylspiro[aziridine-2,3'(4'H)-[2H]chromene]-4'-one; (2R,3S)-3-Ethyl-2,3-dihydrospiro[azirine-2,1'-isochromene]-4'(4'H)-one; 3-Ethylspiro[aziridine-2,3'(4'H)-[2H]chromene]-4'-one (rel-(2R,3S)-form); Spiro[aziridine-2,3(4H)-[2H-1]benzopyran]-4-one, 3-ethyl-, (2R,3S)-rel-; Aziridine-fused benzopyranone derivative
EINECS	Contact for details

Quality Control

Our Spiro[Aziridine-2,3(4H)-[2H-1]Benzopyran]-4-One, 3-Ethyl-, (2R,3S)-Rel- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure consistent identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), enantiomeric excess (Chiral HPLC or SFC), and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC/SFC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.