Description

6-Chloro-7-Methoxy-9H-Pyrido[3,4-B]Indol-8-Amine is a high-purity, heterocyclic organic compound with the CAS number 431886-96-3, serving as a critical advanced pharmaceutical intermediate (API) and a versatile building block for medicinal chemistry research. Its complex fused-ring structure makes it a valuable scaffold for developing novel therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery. This compound is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on synthesizing innovative small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for targeted cancer therapies and neurological disorders.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Serves as a precursor for developing molecular probes to study biological pathways and enzyme functions.
• Organic Synthesis: A versatile intermediate for constructing complex polycyclic aromatic systems and heterocyclic compounds.
• Academic & Industrial R&D: Utilized in university laboratories and corporate R&D centers for exploratory synthesis and new chemical entity (NCE) development.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the production of clinical trial materials and niche APIs.

Basic Information

Product Name	6-Chloro-7-Methoxy-9H-Pyrido[3,4-B]Indol-8-Amine
CAS No.	431886-96-3
Molecular Formula	C₁₂H₁₀ClN₃O
Molecular Weight	247.68 g/mol
Synonyms	8-Amino-6-chloro-7-methoxy-9H-pyrido[3,4-b]indole; 6-Chloro-7-methoxy-9H-β-carbolin-8-amine; 6-Chloro-7-methoxy-8-amino-9H-pyrido[3,4-b]indole; 431886-96-3; 9H-Pyrido[3,4-b]indol-8-amine, 6-chloro-7-methoxy-; β-Carboline derivative, 6-chloro-7-methoxy-8-amino; 8-Amino-6-chloro-7-methoxy-β-carboline
EINECS	Contact for details

Quality Control

Our 6-Chloro-7-Methoxy-9H-Pyrido[3,4-B]Indol-8-Amine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and is supplied with a detailed Certificate of Analysis (COA). We adhere to cGMP principles where applicable to support our clients' pharmaceutical and advanced research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.