Description

2-Amino-5-Chloro-4-Fluoronitrobenzene is a key halogenated aromatic amine intermediate with significant synthetic utility. Its unique substitution pattern makes it a valuable building block for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is primarily sought by research chemists and process development scientists for the synthesis of active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those containing halogenated aniline or benzimidazole cores.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its halogen and nitro functional groups.
• Dye and Pigment Manufacturing: Serves as a starting material for producing specialized azo dyes and high-performance pigments.
• Material Science Research: Employed in the creation of organic electronic materials and liquid crystals due to its electron-withdrawing nitro group and planar structure.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for constructing complex nitrogen-containing heterocycles.

Basic Information

Item	Details
Product Name	2-Amino-5-Chloro-4-Fluoronitrobenzene
CAS No.	428871-64-1
Molecular Formula	C6H4ClFN2O2
Molecular Weight	190.56 g/mol
Synonyms	5-Chloro-4-fluoro-2-nitroaniline; 2-Nitro-5-chloro-4-fluoroaniline; 4-Fluoro-5-chloro-2-nitroaniline; 2-Amino-4-fluoro-5-chloronitrobenzene; 5-Chloro-4-fluoro-2-nitrobenzenamine; Benzenamine, 5-chloro-4-fluoro-2-nitro-; (5-Chloro-4-fluoro-2-nitrophenyl)amine
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-5-Chloro-4-Fluoronitrobenzene is manufactured under strict quality management protocols. We ensure compliance with relevant industry standards through rigorous in-process and final release testing. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.