Description

2-(2-(Trifluoromethyl)Phenyl)Acetohydrazide is a specialized organic compound featuring a phenylacetohydrazide core substituted with a trifluoromethyl group, a structure that imparts unique physicochemical properties. This compound serves as a valuable pharmaceutical intermediate and research chemical for the synthesis of more complex molecules, particularly in medicinal chemistry. It is primarily utilized by R&D laboratories and chemical manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors seeking to incorporate fluorine-containing motifs into their target compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders or requiring enhanced metabolic stability.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides where the trifluoromethyl group can improve biological activity and environmental persistence.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating specialized ligands used in catalysis or as chelating agents in coordination chemistry.
• Material Science: Investigated as a monomer or additive in the production of advanced polymers with specific thermal or chemical resistance properties.
• Chemical Biology Probe Development: Utilized in academic and industrial research to create molecular probes for studying enzyme function or protein interactions.

Basic Information

Product Name	2-(2-(Trifluoromethyl)Phenyl)Acetohydrazide
CAS No.	428507-91-9
Molecular Formula	C9H9F3N2O
Molecular Weight	218.18 g/mol
Synonyms	2-[2-(Trifluoromethyl)phenyl]acetohydrazide; α-(2-Trifluoromethylphenyl)acetohydrazide; 2-(2-Trifluoromethylphenyl)acetic acid hydrazide; 2-(2-(Trifluoromethyl)phenyl)acetylhydrazine; (2-Trifluoromethylphenyl)acetic hydrazide; Acetohydrazide, 2-[2-(trifluoromethyl)phenyl]-; 428507-91-9
EINECS	Contact for details

Quality Control

Our 2-(2-(Trifluoromethyl)Phenyl)Acetohydrazide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong acids, strong bases, and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.