Description

1-(5-Methyl-Furan-2-Carbonyl)-Piperidine-2-Carboxylic Acid CAS NO 427882-96-0 is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is of significant commercial value for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in areas requiring complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold in R&D for structure-activity relationship (SAR) studies and lead optimization.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and cGMP production of clinical trial materials.
• Protease Inhibitor Development: Its structural motifs make it relevant for research into inhibitors targeting specific enzymatic pathways.
• Chemical Library Synthesis: Employed in the creation of diverse compound libraries for high-throughput screening in drug discovery.
• Academic Research: Used in university and institutional labs for studies in synthetic organic chemistry and heterocyclic chemistry.

Basic Information

Product Name	1-(5-Methyl-Furan-2-Carbonyl)-Piperidine-2-Carboxylic Acid
CAS No.	427882-96-0
Molecular Formula	C12H15NO4
Molecular Weight	237.25 g/mol
Synonyms	1-[(5-Methyl-2-furanyl)carbonyl]-2-piperidinecarboxylic acid; 2-Piperidinecarboxylic acid, 1-[(5-methyl-2-furanyl)carbonyl]-; 1-(5-Methylfuran-2-carbonyl)piperidine-2-carboxylic acid; 1-(5-Methyl-2-furoyl)piperidine-2-carboxylic acid; 5-Methyl-2-furoyl pipecolic acid; (5-Methyl-2-furoyl)pipecolic acid; 427882-96-0; Furan-2-carbonyl piperidine carboxylic acid derivative
EINECS	Contact for details

Quality Control

Our 1-(5-Methyl-Furan-2-Carbonyl)-Piperidine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can align with cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product may be hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use. Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.