Description

3-Chloro-6-Methoxyquinolin-4-Ol CAS NO 426842-72-0 is a high-purity quinoline derivative, a crucial building block in advanced organic synthesis. Its unique halogenated and methoxylated structure makes it a versatile intermediate for developing active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for its role in creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in anticancer, antimicrobial, and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides due to its bioactive quinoline core.
• Material Science Research: Serves as a precursor for organic light-emitting diodes (OLEDs), liquid crystals, and other functional organic materials.
• Chemical Research: Employed in academic and industrial R&D for studying structure-activity relationships (SAR) and developing novel synthetic methodologies.
• Dye and Pigment Intermediate: Acts as a building block for synthesizing complex quinoline-based dyes and colorants.

Basic Information

Product Name	3-Chloro-6-Methoxyquinolin-4-Ol
CAS No.	426842-72-0
Molecular Formula	C₁₀H₈ClNO₂
Molecular Weight	209.63 g/mol
Synonyms	4-Hydroxy-3-chloro-6-methoxyquinoline; 3-Chloro-6-methoxy-4-quinolinol; 3-Chloro-6-methoxyquinolin-4-ol; 6-Methoxy-3-chloro-4-hydroxyquinoline; 3-Chloro-6-methoxy-4-hydroxyquinoline; 4-Quinolinol, 3-chloro-6-methoxy-; 3-Chloro-6-methoxy-1H-quinolin-4-one (tautomer)
EINECS	Contact for details

Quality Control

Our 3-Chloro-6-Methoxyquinolin-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.