Description

8-Chloro-2-Methylquinolin-5-Ol is a high-purity quinoline derivative serving as a critical synthetic intermediate in advanced organic chemistry. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients and functional materials. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for process development and scale-up.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting neurological and anti-infective pathways.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides due to its bioactive quinoline core.
• Material Science Precursor: Serves as a monomer or ligand in the creation of organic semiconductors, metal-organic frameworks (MOFs), and luminescent materials.
• Chemical Synthesis: Versatile intermediate for constructing more complex heterocyclic compounds through further functionalization reactions like cross-coupling.
• Analytical Reference Standard: Employed as a certified reference material (CRM) for quality control and method validation in analytical laboratories.

Basic Information

Product Name	8-Chloro-2-Methylquinolin-5-Ol
CAS No.	420786-78-3
Molecular Formula	C₁₀H₈ClNO
Molecular Weight	193.63 g/mol
Synonyms	5-Hydroxy-8-chloro-2-methylquinoline; 8-Chloro-2-methyl-5-quinolinol; 8-Chloro-2-methylquinolin-5-ol; 2-Methyl-8-chloroquinolin-5-ol; 420786-78-3; Quinolin-5-ol, 8-chloro-2-methyl-; 8-Chloro-2-methyl-5-hydroxyquinoline
EINECS	Contact for details

Quality Control

Our 8-Chloro-2-Methylquinolin-5-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere for long-term preservation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.