Description

2-Fluorocyclopropan-1-Amine4-Methylbenzenesulfonate is a high-purity, specialty organic salt with significant utility in advanced chemical synthesis. This compound serves as a critical building block for the development of novel pharmaceuticals and agrochemicals, particularly where the introduction of a fluorinated cyclopropane moiety is required. It is primarily sought by research institutions and industrial R&D departments engaged in medicinal chemistry, process development, and the creation of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) with fluorinated cyclopropane structures, which can enhance metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the unique biological activity of the fluorocyclopropane ring.
• Medicinal Chemistry: A versatile scaffold for structure-activity relationship (SAR) studies and the discovery of new drug candidates in various therapeutic areas.
• Chemical Synthesis: Serves as a protected amine synthon for introducing the 2-fluorocyclopropan-1-amine group into more complex molecular architectures under controlled conditions.
• Process Chemistry & Scale-up: Employed in route scouting and optimization for the commercial-scale production of fine chemicals and target molecules.

Basic Information

Product Name	2-Fluorocyclopropan-1-Amine4-Methylbenzenesulfonate
CAS No.	417725-06-5
Molecular Formula	C10H14FNO3S
Molecular Weight	247.29 g/mol
Synonyms	2-Fluorocyclopropan-1-amine p-toluenesulfonate; 1-Amino-2-fluorocyclopropane tosylate; 2-Fluorocyclopropanamine 4-methylbenzenesulfonate; (1-Amino-2-fluorocyclopropyl) tosylate; 2-Fluorocyclopropylamine tosylate salt; 2-Fluoro-1-aminocyclopropane p-toluenesulfonic acid salt; 2-Fluorocyclopropan-1-aminium 4-methylbenzenesulfonate
EINECS	Contact for details

Quality Control

Our 2-Fluorocyclopropan-1-Amine4-Methylbenzenesulfonate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture. Certificates of Analysis (COA) documenting full specifications are provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.