Description

6-Bromo-1-Methyl-1H-Quinolin-4-One is a versatile brominated quinolinone derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its unique halogenated heterocyclic structure, which is essential for constructing complex molecules with targeted biological and material properties. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting kinase inhibition or other enzyme-related pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides due to its bioactive quinolinone core.
• Material Science: Serves as a precursor for organic light-emitting diodes (OLEDs) and other electronic materials where bromine acts as a handle for further functionalization.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the quinolinone moiety into more complex molecular architectures.
• Academic & R&D: A valuable reagent for medicinal chemistry programs and methodological studies in universities and corporate R&D laboratories.

Basic Information

Product Name	6-Bromo-1-Methyl-1H-Quinolin-4-One
CAS No.	414894-40-9
Molecular Formula	C₁₀H₈BrNO
Molecular Weight	238.08 g/mol
Synonyms	6-Bromo-1-methylquinolin-4(1H)-one; 6-Bromo-1-methyl-4-quinolone; 4(1H)-Quinolinone, 6-bromo-1-methyl-; 1-Methyl-6-bromo-4-quinolone; 6-Bromo-1-methyl-1,4-dihydroquinolin-4-one
EINECS	Contact for details

Quality Control

Our 6-Bromo-1-Methyl-1H-Quinolin-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment ensures the material meets the high standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.