Description

1,8-Bis(4-((1,4,8,11-Tetraazacyclotetradecan-1-Yl)Methyl)Benzyl)-1,4,8,11-Tetraazacyclotetradecane is a sophisticated macrocyclic polyamine ligand, valued for its exceptional metal ion chelating properties and structural versatility. This compound is critical for advanced research and development in fields requiring precise molecular recognition and stable complex formation. It is primarily utilized by researchers and manufacturers in pharmaceutical development, diagnostic imaging, catalysis, and materials science.

Application

• Pharmaceutical Research & Development: As a key precursor or building block for novel metal-based therapeutic agents, including anticancer and antimicrobial drugs.
• Diagnostic Imaging Agents: Chelation of radionuclides (e.g., Gallium-68, Copper-64) for use in Positron Emission Tomography (PET) and Single-Photon Emission Computed Tomography (SPECT) imaging.
• Catalysis: Serving as a ligand to create highly active and selective transition metal catalysts for organic synthesis and polymerization reactions.
• Materials Science: Functionalization of surfaces and nanoparticles for sensor development, separation technologies, and advanced polymeric materials.
• Chemical Biology & Biochemistry: Study of metal ion transport, enzyme mimics, and the development of fluorescent or luminescent probes for cellular imaging.
• Wastewater Treatment: Potential application in the selective removal and recovery of heavy metal ions from industrial effluents.

Basic Information

Item	Detail
Product Name	1,8-Bis(4-((1,4,8,11-Tetraazacyclotetradecan-1-Yl)Methyl)Benzyl)-1,4,8,11-Tetraazacyclotetradecane
CAS No.	414858-02-9
Molecular Formula	C44H84N12
Molecular Weight	757.23 g/mol
Synonyms	1,8-Bis[4-[(1,4,8,11-tetraazacyclotetradecan-1-yl)methyl]benzyl]-1,4,8,11-tetraazacyclotetradecane; TACN-based bis-macrocyclic ligand; Cross-bridged tetraamine ligand; 1,8-Bis(4-(cyclam-1-ylmethyl)benzyl)cyclam; 1,8-Bis(p-(cyclam-1-ylmethyl)benzyl)cyclam; Bifunctional Cyclam Derivative; Polyazamacrocycle Dimer; 414858-02-9
EINECS	Contact for details

Quality Control

Our 1,8-Bis(4-((1,4,8,11-Tetraazacyclotetradecan-1-Yl)Methyl)Benzyl)-1,4,8,11-Tetraazacyclotetradecane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and structural confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using a desiccator or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.