Description

3-(2,3-Difluorophenyl)Propionic Acid is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. Its value lies in the unique reactivity and electronic properties imparted by the difluorophenyl moiety, which is crucial for modulating the biological activity and physicochemical characteristics of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential drug candidates and specialty crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance lipophilicity, metabolic stability, and binding affinity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated aromatic cores for electronic materials, contributing to improved performance in display and lighting technologies.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological processes and protein interactions.
• Polymer Modification: Acts as a monomer or modifier to introduce fluorine-containing side chains into polymers, altering surface properties, chemical resistance, and durability.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3-(2,3-Difluorophenyl)Propionic Acid
CAS No.	412961-26-3
Molecular Formula	C9H8F2O2
Molecular Weight	186.16 g/mol
Synonyms	2,3-Difluorohydrocinnamic Acid; 3-(2,3-Difluorophenyl)propanoic Acid; β-(2,3-Difluorophenyl)propionic Acid; (2,3-Difluorophenyl)propionic Acid; 2,3-Difluorobenzene propanoic acid; 3-(2,3-Difluorophenyl)propionic acid; 412961-26-3; 3-(2,3-Difluorophenyl)propanoic acid
EINECS	Contact for details

Quality Control

Our 3-(2,3-Difluorophenyl)Propionic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with ISO standards and the requirements of GMP environments for non-API intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and heat sources. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.