Description

3-Acetyl-8-Chloro-2-Phenylquinolin-4(1H)-One is a high-value, multi-functional quinoline derivative that serves as a critical advanced intermediate in modern organic synthesis. Its unique molecular architecture, featuring acetyl, chloro, and phenyl substituents on the quinolinone core, makes it an indispensable building block for creating complex molecules with targeted properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for applications in oncology, anti-infectives, and central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a monomer or additive in the research of advanced organic electronic materials, such as OLEDs or conductive polymers.
• Dye & Pigment Synthesis: Acts as a core structure for creating novel quinoline-based dyes and functional pigments with specific light-absorption properties.
• Academic & R&D: Employed in universities and corporate R&D labs for methodological studies in heterocyclic chemistry and as a scaffold for combinatorial library generation.
• Coordination Chemistry: Can function as a ligand for metal complexes in catalytic and sensing applications due to its potential donor sites.

Basic Information

Product Name	3-Acetyl-8-Chloro-2-Phenylquinolin-4(1H)-One
CAS No.	412336-76-6
Molecular Formula	C17H12ClNO2
Molecular Weight	297.74 g/mol
Synonyms	8-Chloro-3-acetyl-2-phenyl-1,4-dihydroquinolin-4-one; 3-Acetyl-8-chloro-2-phenyl-1H-quinolin-4-one; 8-Chloro-3-acetyl-2-phenylquinolin-4(1H)-one; 2-Phenyl-8-chloro-3-acetyl-4-quinolone; 412336-76-6; 3-Acetyl-8-chloro-2-phenyl-4(1H)-quinolinone
EINECS	Contact for details

Quality Control

Our 3-Acetyl-8-Chloro-2-Phenylquinolin-4(1H)-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure consistent quality and batch-to-batch reproducibility. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.