Description

(9H-Fluoren-9-Yl)Methyl 4-(4-Aminophenyl)Piperazine-1-Carboxylate is a high-purity, specialized organic building block of significant interest in advanced pharmaceutical and agrochemical research. Its core value lies in its bifunctional molecular structure, which incorporates both a fluorenylmethyloxycarbonyl (Fmoc)-like protecting group and a reactive aromatic amine, making it a versatile intermediate for constructing complex molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical industry for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for CNS-targeting therapeutics and receptor modulators.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its piperazine and aniline motifs.
• Peptide & Polymer Chemistry: Serves as a protected amine derivative or a monomer unit in the synthesis of specialized polymers and peptide conjugates.
• Chemical Biology & Proteomics: Employed as a reagent or linker in the design of probes, inhibitors, and affinity tags for studying biological systems.
• Material Science: Potential use as a precursor for functionalized organic materials and dyes due to its conjugated fluorene system.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses producing bespoke compounds for client R&D projects.

Basic Information

Product Name	(9H-Fluoren-9-Yl)Methyl 4-(4-Aminophenyl)Piperazine-1-Carboxylate
CAS No.	412331-98-7
Molecular Formula	C26H25N3O2
Molecular Weight	411.50 g/mol
Synonyms	4-(4-Aminophenyl)-1-[(9H-fluoren-9-ylmethoxy)carbonyl]piperazine; 1-[(9H-Fluoren-9-ylmethoxy)carbonyl]-4-(4-aminophenyl)piperazine; Fmoc-4-(4-Aminophenyl)piperazine; 4-(4-Aminophenyl)piperazine-1-carboxylic acid 9H-fluoren-9-ylmethyl ester; 1-N-Fmoc-4-(4-aminophenyl)piperazine; 412331-98-7; 4-(4-Aminophenyl)-1-(9-fluorenylmethyloxycarbonyl)piperazine
EINECS	Contact for details

Quality Control

Our (9H-Fluoren-9-Yl)Methyl 4-(4-Aminophenyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening the primary container to maximize shelf life. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.