Description

trans-4-Aminocyclohexyl)(Morpholino)Methanone is a high-purity, functionalized cyclohexane derivative featuring both an amine and a morpholine amide group. This unique bifunctional structure makes it a valuable and versatile pharmaceutical intermediate and organic building block for medicinal chemistry research and process development. It is primarily utilized by R&D chemists and process scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and metabolic disease targets.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to introduce both hydrogen-bonding and conformational rigidity into molecular scaffolds.
• Ligand and Catalyst Development: Serves as a precursor for creating novel ligands in asymmetric catalysis or for metal-organic frameworks (MOFs).
• Agrochemical Synthesis: Intermediate in the development of new herbicides, fungicides, or plant growth regulators.
• Peptidomimetics: The amide linkage and amine functionality make it suitable for constructing peptidomimetic compounds.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific, high-value chiral amines.

Basic Information

Product Name	trans-4-Aminocyclohexyl)(Morpholino)Methanone
CAS No.	412291-29-3
Molecular Formula	C11H20N2O2
Molecular Weight	212.29 g/mol
Synonyms	trans-4-Aminocyclohexanecarboxylic acid morpholide; 4-Morpholinocarbonylcyclohexylamine (trans); N-(trans-4-Aminocyclohexyl)morpholine-4-carboxamide; (trans-4-Aminocyclohexyl)-morpholin-4-ylmethanone; Morpholine, 4-[(trans-4-aminocyclohexyl)carbonyl]-; 412291-29-3; (4-Aminocyclohexyl)(morpholino)methanone (trans)
EINECS	Contact for details

Quality Control

Our trans-4-Aminocyclohexyl)(Morpholino)Methanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (trans isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.