Description

4-Bromo-1-(2-Methyl-Benzenesulfonyl)-1H-Indole is a high-purity, functionalized indole derivative designed for advanced chemical synthesis. This compound serves as a critical building block in pharmaceutical research and development, enabling the construction of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the indole scaffold's bioactivity.
• Material Science: Serves as a monomer or functional additive in the creation of advanced polymers and organic electronic materials.
• Chemical Biology: Employed as a probe or labeling reagent in biochemical assays and proteomics research.
• Catalyst Ligand Synthesis: Utilized to construct sophisticated ligands for asymmetric catalysis and transition metal complexes.
• Academic & Contract Research: Essential for methodological development and exploratory synthesis in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	4-Bromo-1-(2-Methyl-Benzenesulfonyl)-1H-Indole
CAS No.	412048-78-3
Molecular Formula	C15H12BrNO2S
Molecular Weight	350.23 g/mol
Synonyms	4-Bromo-1-(o-tolylsulfonyl)-1H-indole; 1H-Indole, 4-bromo-1-[(2-methylphenyl)sulfonyl]-; 4-Bromo-1-(2-methylbenzenesulfonyl)indole; 4-Bromo-1-tosyl-1H-indole (common misnomer); 4-Bromo-1-(2-methylphenylsulfonyl)indole; 412048-78-3; 4-Bromo-1-(2-toluenesulfonyl)indole
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-1-(2-Methyl-Benzenesulfonyl)-1H-Indole is manufactured and tested under strict quality management systems. We guarantee high chemical purity and consistency, with comprehensive analysis performed using advanced techniques including HPLC, GC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.