Description

Pyrrolo[1,2-A]Pyrazine-1,4-Dione, Hexahydro-8-Methyl-, (8S,8As)- (9Ci) is a high-purity, stereochemically defined heterocyclic compound of significant interest in advanced organic synthesis. Its complex fused-ring structure makes it a valuable key chiral building block for the development of novel pharmacologically active molecules. This compound is primarily utilized by research institutions and pharmaceutical R&D departments engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral scaffold in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and anti-infective targets.
• Medicinal Chemistry Research: Used as a versatile building block for constructing complex molecular libraries in structure-activity relationship (SAR) studies.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Acts as a starting material or intermediate in catalytic asymmetric transformations due to its defined stereocenters.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Academic Research: Applied in university and institutional labs for methodological development in heterocyclic and synthetic organic chemistry.

Basic Information

Product Name	Pyrrolo[1,2-A]Pyrazine-1,4-Dione, Hexahydro-8-Methyl-, (8S,8As)- (9Ci)
CAS No.	411225-58-6
Molecular Formula	C8H12N2O2
Molecular Weight	168.19 g/mol
Synonyms	(8S,8aS)-Hexahydro-8-methylpyrrolo[1,2-a]pyrazine-1,4-dione; (8S,8aS)-8-Methylhexahydro-1H,5H-pyrrolo[1,2-a]pyrazine-1,4-dione; Hexahydro-8-methylpyrrolo[1,2-a]pyrazine-1,4-dione, (8S,8aS)-; (8S,8aS)-8-Methylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione; Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-8-methyl-, (8S,8aS)-; CAS 411225-58-6.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development chemicals. All batches are characterized using advanced analytical techniques including HPLC, NMR, and MS to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing lot-specific results are available upon request. We adhere to a strict quality management system to guarantee batch-to-batch consistency and reliable performance in your synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.