Description

N,N'-Bis-Boc-N''-Aminoethoxyguanidine is a high-purity, protected guanidine derivative used as a critical building block in advanced organic synthesis. Its primary value lies in enabling the controlled introduction of guanidine functionality, a key pharmacophore, into complex molecular architectures under mild conditions. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for developing novel peptide mimetics, protease inhibitors, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of guanidine-containing drug candidates, including antiviral and cardiovascular agents.
• Peptidomimetic Chemistry: Used to incorporate guanidine groups into peptide backbones to enhance binding affinity and metabolic stability.
• Protease Inhibitor Development: Serves as a precursor for creating potent inhibitors of serine and cysteine proteases.
• Bioconjugation & Labeling: The protected amino and guanidine groups allow for selective deprotection and functionalization in bioconjugation strategies.
• Chemical Biology Probes: Employed in the construction of molecular probes to study enzyme mechanisms and protein-protein interactions.
• Agrochemical Research: Used in the discovery of new active ingredients that utilize the guanidine motif for biological activity.

Basic Information

Item	Details
Product Name	N,N'-Bis-Boc-N''-Aminoethoxyguanidine
CAS No.	409081-80-7
Molecular Formula	C₁₉H₃₆N₄O₆
Molecular Weight	416.52 g/mol
Synonyms	1,1'-(Ethane-1,2-diyl)bis(3-((tert-butoxycarbonyl)amino)guanidine); 2-((Bis((tert-butoxycarbonyl)amino)methylene)amino)ethylcarbamic Acid tert-Butyl Ester; N,N-Bis-Boc-N''-Aminoethoxyguanidine; Aminoethoxyguanidine Bis-Boc Derivative; Boc-Protected Aminoethoxyguanidine; tert-Butyl N-[2-[[(Z)-[bis[(tert-butoxycarbonyl)amino]methylidene]amino]ethyl]carbamate
EINECS	Contact for details

Quality Control

Every batch of N,N'-Bis-Boc-N''-Aminoethoxyguanidine is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and cGMP manufacturing. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity (typically ≥95% by HPLC), and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.