Description

1-Azabicyclo[2.2.2]Octan-3-One, 2-Chloro- is a specialized bicyclic organic compound featuring a quinuclidine core structure with a ketone and a chloro substituent. This molecule serves as a high-value building block in advanced organic synthesis, particularly for constructing complex nitrogen-containing pharmacophores. It is primarily needed by pharmaceutical R&D and fine chemical synthesis teams developing novel active ingredients and catalysts.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, especially those targeting neurological disorders.
• Agrochemical Research: Building block for developing novel herbicides and pesticides with specific mode-of-action.
• Catalyst Ligand Synthesis: Used to create sophisticated chiral ligands for asymmetric catalysis.
• Academic & Institutional Research: Valuable reagent for methodological studies in heterocyclic and medicinal chemistry.
• Material Science: Potential monomer or additive for advanced polymeric materials with specific functional properties.

Basic Information

Product Name	1-Azabicyclo[2.2.2]Octan-3-One, 2-Chloro-
CAS No.	409070-90-2
Molecular Formula	C7H10ClNO
Molecular Weight	159.61 g/mol
Synonyms	2-Chloro-1-azabicyclo[2.2.2]octan-3-one; 2-Chloroquinuclidin-3-one; 3-Quinuclidinone, 2-chloro-; 2-Chloro-3-quinuclidinone; 1-Azabicyclo[2.2.2]octan-3-one, 2-chloro-; 409070-90-2; 2-Chloro-1-aza-bicyclo[2.2.2]octan-3-one
EINECS	Contact for details

Quality Control

Our production of 1-Azabicyclo[2.2.2]Octan-3-One, 2-Chloro- adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as verified by HPLC, GC, NMR, and IR spectroscopy. Our quality system is designed to meet the exacting standards of GMP and ISO guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials. The product is light-sensitive and should be handled accordingly.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.