Description

3'-(Trifluoromethyl)[1,1'-Biphenyl]-2-Carboxylic Acid is a high-value biphenyl carboxylic acid derivative distinguished by the presence of a trifluoromethyl group, which imparts unique electronic and steric properties. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily required by R&D and production teams in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used as a precursor for developing new-generation herbicides and fungicides, where the trifluoromethyl group enhances bioactivity and environmental stability.
• Ligand & Catalyst Development: Serves as a backbone for creating sophisticated ligands in asymmetric catalysis and organometallic chemistry.
• Material Science Precursor: Employed in the research and production of advanced organic electronic materials, such as OLEDs and semiconductors.
• Chemical Research & Development: A valuable building block for constructing complex polycyclic aromatic systems and fluorinated compounds in academic and industrial R&D labs.

Basic Information

Product Name	3'-(Trifluoromethyl)[1,1'-Biphenyl]-2-Carboxylic Acid
CAS No.	408367-99-7
Molecular Formula	C14H9F3O2
Molecular Weight	266.22 g/mol
Synonyms	[1,1'-Biphenyl]-2-carboxylic acid, 3'-(trifluoromethyl)-; 2-Biphenylcarboxylic acid, 3'-(trifluoromethyl)-; 3'-(Trifluoromethyl)biphenyl-2-carboxylic acid; 2-Carboxy-3'-(trifluoromethyl)biphenyl; 3'-Trifluoromethyl-2-biphenylcarboxylic acid; 2-(3-(Trifluoromethyl)phenyl)benzoic acid; 3'-Trifluoromethylbiphenyl-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 3'-(Trifluoromethyl)[1,1'-Biphenyl]-2-Carboxylic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content. We provide full traceability and Certificates of Analysis (COA) are available upon request to ensure compliance with your specific R&D or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.