Description

2-Quinolinecarboxylic Acid, 3-Chloro-4-Hydroxy-, Ethyl Ester is a high-purity, functionalized quinoline derivative that serves as a critical synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in advanced pharmaceutical research and fine chemical synthesis. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to develop new active ingredients or functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibitors or receptor modulators.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or pesticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic systems or metal-organic frameworks (MOFs).
• Organic Electronic Materials: Potential starting material for the synthesis of quinoline-based compounds used in OLEDs or other optoelectronic applications.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target identification.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex heterocycles.

Basic Information

Product Name	2-Quinolinecarboxylic Acid, 3-Chloro-4-Hydroxy-, Ethyl Ester
CAS No.	408327-43-5
Molecular Formula	C₁₂H₁₀ClNO₃
Molecular Weight	251.67 g/mol
Synonyms	Ethyl 3-Chloro-4-hydroxyquinoline-2-carboxylate; 3-Chloro-4-hydroxy-2-quinolinecarboxylic Acid Ethyl Ester; 3-Chloro-4-hydroxyquinoline-2-carboxylic acid ethyl ester; 2-Quinolinecarboxylic acid, 3-chloro-4-hydroxy-, ethyl ester; Quinoline-2-carboxylic acid, 3-chloro-4-hydroxy-, ethyl ester
EINECS	Contact for details

Quality Control

Our 2-Quinolinecarboxylic Acid, 3-Chloro-4-Hydroxy-, Ethyl Ester is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be stored away from light to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.