Description

(3R,5R)-1-(4-Hydroxy-3-Methoxyphenyl)-7-(3,4-Dihydroxyphenyl)Heptane-3,5-Diol is a high-purity, stereochemically defined polyphenolic compound of significant research and development interest. This compound matters as a key intermediate and reference standard for synthesizing and studying bioactive natural product derivatives, particularly those with antioxidant and anti-inflammatory properties. It is primarily needed by pharmaceutical R&D laboratories, nutraceutical ingredient manufacturers, and academic institutions focused on medicinal chemistry and pharmacology.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block for the synthesis of complex bioactive molecules and potential drug candidates.
• Reference Standard: Used as a high-purity analytical standard for quality control and method validation in HPLC and LC-MS assays.
• Biochemical Research: Employed in in vitro studies to investigate mechanisms related to oxidative stress, inflammation, and cell signaling pathways.
• Nutraceutical Development: Acts as a precursor or model compound for developing standardized botanical extracts and dietary supplements.
• Medicinal Chemistry: Provides a core structure for structure-activity relationship (SAR) studies to optimize pharmacological profiles.
• Academic & Contract Research: Essential for university labs and CROs conducting fundamental research on polyphenol chemistry and bioactivity.

Basic Information

Product Name	(3R,5R)-1-(4-Hydroxy-3-Methoxyphenyl)-7-(3,4-Dihydroxyphenyl)Heptane-3,5-Diol
CAS No.	408324-13-0
Molecular Formula	C20H26O6
Molecular Weight	362.42 g/mol
Synonyms	(3R,5R)-1-(4-Hydroxy-3-methoxyphenyl)-7-(3,4-dihydroxyphenyl)heptane-3,5-diol; (3R,5R)-7-(3,4-Dihydroxyphenyl)-1-(4-hydroxy-3-methoxyphenyl)heptane-3,5-diol; 1,7-Bis(aryl)heptane-3,5-diol derivative; Curcuminoid analog; Dihydrocurcumin derivative; Tetrahydrocurcumin stereoisomer; (R,R)-Tetrahydrocurcuminol
EINECS	Contact for details

Quality Control

Our (3R,5R)-1-(4-Hydroxy-3-Methoxyphenyl)-7-(3,4-Dihydroxyphenyl)Heptane-3,5-Diol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for stereochemical purity and identity confirmation, to ensure compliance with research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing purity, chiral excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label or COA. The compound is easily oxidized and moisture-sensitive; ensure the container is sealed immediately after use and stored in a cool, dry place.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (3R,5R)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.