Description

4-Ethynyl-3-Methyl-Phenol is a versatile phenolic building block featuring both a hydroxyl group and an ethynyl moiety, enabling diverse chemical transformations. This compound is valued for its role as a key intermediate in the synthesis of advanced materials and complex organic molecules. It is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial synthon in the development of new active pharmaceutical ingredients (APIs), particularly for molecules requiring a phenolic ethynyl scaffold.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers, resins, and high-performance coatings.
• Ligand & Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalytic systems.
• Chemical Research: A valuable tool for academic and industrial R&D in organic synthesis, including click chemistry and Sonogashira coupling reactions.
• Fine Chemical Production: Utilized as a building block for synthesizing complex fragrances, dyes, and other high-value fine chemicals.

Basic Information

Product Name	4-Ethynyl-3-Methyl-Phenol
CAS No.	408319-96-0
Molecular Formula	C9H8O
Molecular Weight	132.16 g/mol
Synonyms	3-Methyl-4-ethynylphenol; 4-Ethynyl-3-methylphenol; 4-Ethynyl-m-cresol; 2-Methyl-4-ethynylphenol; 3-Methyl-4-ethynylphenol; Phenol, 4-ethynyl-3-methyl-; 4-Ethynyl-3-methyl hydroxybenzene
EINECS	Contact for details

Quality Control

Our 4-Ethynyl-3-Methyl-Phenol is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with each shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Keep away from oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.