Description

1,3-Dioxan-4-Ol,5,5-Dimethyl-2-(1-Methylethyl)-,(2R,4S)-Rel-(9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its unique dioxane ring structure and defined stereochemistry make it a valuable intermediate for constructing complex molecules with precise spatial orientation. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, chiral catalysts, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in projects requiring specific stereochemical control.
• Agrochemical Synthesis: Used in the development of advanced, stereoselective pesticides and herbicides where the biological activity is highly dependent on molecular configuration.
• Catalyst & Ligand Development: Serves as a precursor for synthesizing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals for electronics, materials science, and fragrance applications.
• Academic & Industrial Research: A valuable tool for chemists in universities and corporate R&D labs exploring new synthetic methodologies and reaction pathways.

Basic Information

Product Name	1,3-Dioxan-4-Ol,5,5-Dimethyl-2-(1-Methylethyl)-,(2R,4S)-Rel-(9Ci)
CAS No.	406956-07-8
Molecular Formula	C9H18O3
Molecular Weight	174.24 g/mol
Synonyms	(2R,4S)-rel-5,5-Dimethyl-2-(propan-2-yl)-1,3-dioxan-4-ol; (rel)-(2R,4S)-5,5-Dimethyl-2-isopropyl-1,3-dioxan-4-ol; 5,5-Dimethyl-2-(1-methylethyl)-1,3-dioxan-4-ol, (2R,4S)-rel-; 1,3-Dioxan-4-ol, 5,5-dimethyl-2-(1-methylethyl)-, (2R,4S)-rel-; Chiral 1,3-dioxane derivative; Isopropyl-substituted dioxanol
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality management protocols to ensure batch-to-batch consistency and high chemical purity. Every lot is characterized using advanced analytical techniques including chiral HPLC, GC, NMR, and optical rotation measurement to confirm identity, stereochemical purity, and assay. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support development and cGMP manufacturing needs with appropriate documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). For long-term storage, consider packing under an inert gas such as nitrogen or argon. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de (diastereomeric excess)
Optical Rotation	Specific range provided on COA
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.