Description

(2S)-1,4-Dioxan-2-Yl-Methanol is a chiral, non-racemic chemical building block featuring a dioxane ring with a hydroxymethyl substituent. This compound matters as a versatile synthon for the asymmetric synthesis of complex molecules, particularly in the development of pharmaceuticals and fine chemicals. It is needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce chiral, oxygenated motifs into their target structures.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting the central nervous system or as a component of complex polyether structures.
• Ligand and Catalyst Synthesis: Serves as a starting material for the preparation of chiral ligands used in asymmetric catalysis, such as for hydrogenation or oxidation reactions.
• Polymer Chemistry: Can be utilized as a monomer or co-monomer for creating novel polymers with specific chiral or hydrophilic properties.
• Agrochemical Research: Employed in the development of chiral herbicides, fungicides, or plant growth regulators where stereochemistry impacts biological activity.
• Material Science: Used in the research of advanced materials, including liquid crystals or chiral stationary phases for chromatography.
• Flavor and Fragrance Industry: Acts as a potential intermediate for the synthesis of chiral aroma chemicals and flavorants.

Basic Information

Product Name	(2S)-1,4-Dioxan-2-Yl-Methanol
CAS No.	406913-93-7
Molecular Formula	C5H10O3
Molecular Weight	118.13 g/mol
Synonyms	(S)-(+)-1,4-Dioxan-2-ylmethanol; (S)-2-(Hydroxymethyl)-1,4-dioxane; (2S)-2-(Hydroxymethyl)-1,4-dioxane; (S)-1,4-Dioxane-2-methanol; (S)-Dioxanyl methanol; L-1,4-Dioxan-2-ylmethanol; (S)-configuration 1,4-Dioxan-2-yl-Methanol
EINECS	Contact for details

Quality Control

Our (2S)-1,4-Dioxan-2-Yl-Methanol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.