Description

3-[5-[3,5-Di(Trifluoromethyl)Phenyl]-2-Furyl]Acrylic Acid is a high-value, fluorinated organic building block characterized by its unique furan-acrylic acid core flanked by electron-withdrawing trifluoromethyl groups. This molecular architecture makes it a critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs) requiring specific electronic and steric properties. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with enhanced bioavailability and stability.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel small-molecule drugs, particularly in kinase inhibitor and anti-inflammatory agent research.
• Agrochemical Synthesis: Used in creating advanced herbicides and fungicides where the trifluoromethyl groups improve lipophilicity and biological activity.
• Ligand & Catalyst Development: Serves as a precursor for sophisticated ligands in transition metal catalysis, enabling challenging cross-coupling reactions.
• Material Science Research: Building block for organic electronic materials, such as semiconductors and light-emitting diodes (OLEDs), due to its conjugated system.
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research focused on introducing perfluoroalkyl motifs into complex scaffolds.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific molecule production.

Basic Information

Product Name	3-[5-[3,5-Di(Trifluoromethyl)Phenyl]-2-Furyl]Acrylic Acid
CAS No.	406725-93-7
Molecular Formula	C₁₆H₈F₆O₃
Molecular Weight	362.23 g/mol
Synonyms	3-[5-[3,5-Bis(trifluoromethyl)phenyl]-2-furyl]acrylic acid; 3-[5-(3,5-Bis(trifluoromethyl)phenyl)furan-2-yl]acrylic acid; 3-[5-(3,5-Di(trifluoromethyl)phenyl)-2-furyl]-2-propenoic acid; 2-Furanacrylic acid, 5-[3,5-bis(trifluoromethyl)phenyl]-; (E)-3-(5-(3,5-Bis(trifluoromethyl)phenyl)furan-2-yl)acrylic acid; CAS 406725-93-7
EINECS	Contact for details

Quality Control

Every batch of 3-[5-[3,5-Di(Trifluoromethyl)Phenyl]-2-Furyl]Acrylic Acid is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical R&D and scale-up processes. Certificates of Analysis (COA) with detailed HPLC/GC and NMR results are available for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.