Description

Hydrazinecarboxylic Acid, 2-(2-Propynyl)-, 1,1-Dimethylethyl Ester (9Ci) is a specialized organic building block featuring both a propargyl and a tert-butyl carbazate protecting group. This compound matters as a versatile synthon for the controlled introduction of hydrazine functionality in complex organic synthesis, offering chemists a handle for selective deprotection and further functionalization. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for constructing novel heterocycles and active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those containing nitrogen heterocycles like pyrazoles and triazoles.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators that require hydrazine-based scaffolds.
• Peptide Chemistry & Bioconjugation: The propargyl group enables click chemistry reactions (e.g., CuAAC) for site-specific labeling and conjugation of biomolecules.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of advanced polymers with tailored properties.
• Academic & Contract Research: A valuable reagent for methodological studies in organic synthesis and the exploration of new catalytic processes.

Basic Information

Product Name	Hydrazinecarboxylic Acid, 2-(2-Propynyl)-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	406683-19-0
Molecular Formula	C9H16N2O2
Molecular Weight	184.24 g/mol
Synonyms	tert-Butyl 2-(prop-2-yn-1-yl)hydrazine-1-carboxylate; N-(tert-Butoxycarbonyl)-N'-propargylhydrazine; 1-Boc-2-propargylhydrazine; Boc-NH-NH-CH2-C≡CH; 2-Propargyl-1-Boc-hydrazine; tert-Butyl N-(prop-2-yn-1-yl)carbazate; Propargyl Boc-hydrazine
EINECS	Contact for details

Quality Control

Our Hydrazinecarboxylic Acid, 2-(2-Propynyl)-, 1,1-Dimethylethyl Ester (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and purity. For cGMP or other specific regulatory requirements, please contact our technical sales team to discuss available documentation and validation support.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.