Description

n-(3-Fluorophenyl)-2,7,7-Trimethyl-5-Oxo-4-(3-Thienyl)-1,4,5,6,7,8-Hexahydro-3-Quinolinecarboxamide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the research and development of novel therapeutic agents, particularly in medicinal chemistry programs targeting central nervous system (CNS) and other disease pathways. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of complex active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those with quinoline and thiophene pharmacophores.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for developing new therapeutic molecules.
• Active Pharmaceutical Ingredient (API) Development: A crucial precursor in multi-step synthetic routes for potential APIs targeting neurological and other disorders.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis and process development projects.
• Chemical Reference Standard: Can be used as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.
• Academic & Institutional Research: Employed in university and institutional labs for advanced organic synthesis and pharmacological studies.

Basic Information

Item	Details
Product Name	n-(3-Fluorophenyl)-2,7,7-Trimethyl-5-Oxo-4-(3-Thienyl)-1,4,5,6,7,8-Hexahydro-3-Quinolinecarboxamide
CAS No.	406183-09-3
Molecular Formula	C23H23FN2O2S
Molecular Weight	410.50 g/mol
Synonyms	4-(3-Thienyl)-N-(3-fluorophenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydro-3-quinolinecarboxamide; 1,4,5,6,7,8-Hexahydro-N-(3-fluorophenyl)-2,7,7-trimethyl-5-oxo-4-(3-thienyl)-3-quinolinecarboxamide; 406183-09-3; 3-Quinolinecarboxamide, 1,4,5,6,7,8-hexahydro-N-(3-fluorophenyl)-2,7,7-trimethyl-5-oxo-4-(3-thienyl)-
EINECS	Contact for details

Quality Control

Our n-(3-Fluorophenyl)-2,7,7-Trimethyl-5-Oxo-4-(3-Thienyl)-1,4,5,6,7,8-Hexahydro-3-Quinolinecarboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.