Description

2-(4-Bromo-Phenyl)-4,6-Dichloro-Quinazoline is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its unique halogenated quinazoline core, which serves as a critical scaffold for constructing complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, material science, and as a key intermediate in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a versatile precursor in the synthesis of potential drug candidates, particularly kinase inhibitors and other biologically active molecules targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Material Science: Acts as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) due to the presence of reactive bromo and chloro substituents, enabling precise molecular diversification.
• Academic & Contract Research: Essential for fundamental research in heterocyclic chemistry and for contract research organizations (CROs) developing custom synthetic routes.

Basic Information

Product Name	2-(4-Bromo-Phenyl)-4,6-Dichloro-Quinazoline
CAS No.	405933-98-4
Molecular Formula	C14H7BrCl2N2
Molecular Weight	354.03 g/mol
Synonyms	4,6-Dichloro-2-(4-bromophenyl)quinazoline; 2-(4-Bromophenyl)-4,6-dichloroquinazoline; Quinazoline, 2-(4-bromophenyl)-4,6-dichloro-; 4,6-Dichloro-2-(p-bromophenyl)quinazoline; 2-(p-Bromophenyl)-4,6-dichloroquinazoline; 405933-98-4; 4,6-Dichloro-2-(4'-bromophenyl)quinazoline
EINECS	Contact for details

Quality Control

Our 2-(4-Bromo-Phenyl)-4,6-Dichloro-Quinazoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our commitment to quality assurance ensures the material meets the high standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.