Description

2-(4-Bromo-Phenyl)-4-Chloro-6-Methyl-Quinazoline is a high-purity, synthetically versatile quinazoline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized core structure for developing novel compounds with targeted biological or material properties. This intermediate is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the development of kinase inhibitors and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially for oncology and anti-inflammatory targets.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Chemical Biology Probe Development: Employed in creating molecular tools to study enzyme function and cellular signaling pathways.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions, nucleophilic substitutions, and other transformations to create complex heterocyclic systems.
• Material Science Research: Investigated as a component for organic electronic materials due to the quinazoline core's electron-accepting properties.

Basic Information

Product Name	2-(4-Bromo-Phenyl)-4-Chloro-6-Methyl-Quinazoline
CAS No.	405933-97-3
Molecular Formula	C15H10BrClN2
Molecular Weight	333.61 g/mol
Synonyms	4-Chloro-2-(4-bromophenyl)-6-methylquinazoline; 2-(4-Bromophenyl)-4-chloro-6-methylquinazoline; 6-Methyl-2-(4-bromophenyl)-4-chloroquinazoline; Quinazoline, 2-(4-bromophenyl)-4-chloro-6-methyl-; 405933-97-3; 4-Chloro-6-methyl-2-(4-bromophenyl)quinazoline; 2-(p-Bromophenyl)-4-chloro-6-methylquinazoline
EINECS	Contact for details

Quality Control

Our 2-(4-Bromo-Phenyl)-4-Chloro-6-Methyl-Quinazoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with all shipments to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.