Description

1N-Boc 3-(4'-Nitrophenoxy) Pyrrolidine CAS NO 405887-36-7 is a high-purity, advanced pharmaceutical intermediate featuring a protected pyrrolidine scaffold with a nitrophenoxy side chain. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of complex bioactive molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Protease Inhibitor Synthesis: Used in the construction of peptidomimetic frameworks for inhibitors targeting various enzymes.
• Ligand and Scaffold Development: Serves as a core structure for developing novel chemical libraries in high-throughput screening.
• Agrochemical Research: Intermediate in the development of new active ingredients with specific biological activity.
• Academic Research: A valuable reagent for synthetic organic chemistry studies and methodology development in universities and research institutes.
• Custom Synthesis: Starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	1N-Boc 3-(4'-Nitrophenoxy) Pyrrolidine
CAS No.	405887-36-7
Molecular Formula	C15H20N2O5
Molecular Weight	308.33 g/mol
Synonyms	tert-Butyl 3-(4-nitrophenoxy)pyrrolidine-1-carboxylate; 1-Boc-3-(4-nitrophenoxy)pyrrolidine; 1-(tert-Butoxycarbonyl)-3-(4-nitrophenoxy)pyrrolidine; Pyrrolidine, 3-(4-nitrophenoxy)-, 1-(1,1-dimethylethyl) ester; 3-(4-Nitrophenoxy)-1-(tert-butoxycarbonyl)pyrrolidine; 405887-36-7; Boc-3-(4-Nitrophenoxy)pyrrolidine; 1-N-Boc-3-(4'-Nitrophenoxy)pyrrolidine
EINECS	Contact for details

Quality Control

Our 1N-Boc 3-(4'-Nitrophenoxy) Pyrrolidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We adhere to cGMP standards where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.